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Sigal A, Milo R, Cohen A, et al

Pericytes are generally partially detached from endothelial cells in tumor vessels, and the basement membrane is unevenly distributed, leading to increased vessel fragility and risks of hemorrhage [88,89,90]

Meta-analyses of randomized controlled trials suggest that infusion of 300 to 600 mg/day of lipoic acid for two to four weeks significantly reduced the symptoms of diabetic neuropathy to a clinically meaningful degree (55, 74)