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In this case, the B12 shots have started to heal the damaged neurons myelin sheath, but the neural network in which the healed neuron is in, is in a super sensitive state (with extra receptors), so the patient may feel pain or other unpleasant sensations

Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances

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Of particular interest are probiotics which represent live non-pathogenic microorganisms that can restore microbial balance in the gastrointestinal tract upon appropriate administration (18)