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Its extraordinary versatility continues to support ongoing scientific exploration into complex biological repair and systemic adaptation mechanisms

J Ethnopharmacol 302(Pt A):115913

While useful as a simplified framework that characterizes microglia as either pro-inflammatory (M1) or protective/repair-oriented (M2), the classical M1/M2 dichotomy does not fully capture the diverse and dynamic activation states of microglia, which often exist along a phenotypic continuum between pro-inflammatory and protective functions (Tastan and Heneka, 2024

Lin H, Hsu F-C, Baumann BH, Coulter DA, Anderson SA, Lynch DR (2014) Cortical parvalbumin GABAergic deficits with 7 nicotinic acetylcholine receptor deletion: implications for schizophrenia

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