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74 In addition, products that are intended to treat tobacco dependence are not considered MRTPs if they have been approved as a drug or device

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The study evaluated data on 27,459 smokers admitted to 270 hospitals for one of three reasons: a heart attack, bypass surgery or the insertion of a cardiac stent

It is also contraindicated in patients with severe respiratory insufficiency, except in those patients requiring relief of anxiety and/or diminished recall of events while being mechanically ventilated