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Interestingly, the incubation with the antioxidant N-acetylcysteine (NAC) upon treatment with NP4 resulted in reduced levels of apoptosis, suggestive that the cytotoxicity of NP4 is related to intracellular redox homeostasis (Supplementary Fig

Glutathione benefits include the ability to help reduce the appearance of dark spots, age spots, and melasma by inhibiting the enzyme tyrosinase, which is involved in melanin production

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GSTs have emerged as a promising therapeutic target because specific isozymes are overexpressed in a wide variety of tumors and may play a role in the etiology of other diseases, including neurodegenerative diseases, multiple sclerosis, and asthma

Pemble S, Schroeder KR, Spencer SR, Meyer DJ, Hallier E, Bolt HM, Ketterer B, Taylor JB