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Antioxidant therapy as a potential approach to severe influenza-associated complications

Analysis of liver transcriptomic and metabolomic profiles in response to short-term fasting or a high-fat diet revealed divergent responses in liver metabolism of male and female mice

The metabolism and elimination of NAD+ (and its by-products) could be altered in advanced hepatic or renal dysfunction, and high-dose NAD+ might theoretically affect cardiovascular dynamics, so practitioners generally avoid or closely supervise NAD+ use in such settings

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Together, these studies suggest that ascorbate-derived imaging methods may be able to image oxidative stress in vivo