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ACS Cent Sci 6:4153 Soula M, Weber RA, Zilka O, Alwaseem H, La K, Yen F et al (2020) Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
Y250 is located much farther from the disulfide bonds (Cys128-Cys206 in the hinge region between K1 and K2 domains, and Cys211-Cys288, Cys232-Cys271, and Cys260-Cys283 in the K2 domain) than the distances between Y198 and disulfide bonds, Cys149-Cys189 and Cys177-Cys201
when GSH is taken orally, it has low bioavailability and is easily broken down by the stomach and is not effective
Curr Res Food Sci
Feeling Flushed or Dizzy: Can occur during an IV infusion but usually resolves quickly
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