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Currently, numerous researchers are dedicated to the development of LBPs based on engineered bacteria (Table 1), some of which have entered the clinical trial phase and achieved remarkable outcomes

Patients looking for stronger results typically move to semaglutide or tirzepatide options

In studies assessing body composition, the weight lost with semaglutide treatment was reported to come mainly from body fat, with approximately 84.5% of weight loss from fat mass and 15.5% from lean tissue , which can include water, muscle and organs

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